Open AccessThe action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis
Author(s) -
Fabiana P Zarur,
Luiza Vf d'Almeida,
Anna Beatriz Celano Novellino,
Maria Fernanda Reis
Publication year - 2014
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/0974-7753.136756
Subject(s) - medicine , scalp , hypertrichosis , thickening , spinal osteoarthropathy , dermatology , anatomy , pathology , chemistry , polymer science
Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation). We report a case of a patient with the complete form of the disease, and with a unique appearance of the hair shaft and eyelashes. The authors propose a possible mechanism to justify the abnormalities observed in the patient's hair shafts regarding the metabolism of prostaglandins and its relationship with the hair follicle physiological cycle.