The action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis | Zendy

FabianaP Zarur | Zendy; Luiza Ferreira Vieira d'Almeida | Zendy; Anna BeatrizC Novellino | Zendy; Maria FernandaDG Reis | Zendy

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The action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis

Author(s) -

FabianaP Zarur,

Luiza Ferreira Vieira d'Almeida,

Anna BeatrizC Novellino,

Maria FernandaDG Reis

Publication year - 2014

Publication title -

international journal of trichology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.494

H-Index - 22

eISSN - 0974-9241

pISSN - 0974-7753

DOI - 10.4103/0974-7753.136756

Subject(s) - medicine , scalp , hypertrichosis , thickening , spinal osteoarthropathy , dermatology , anatomy , pathology , chemistry , polymer science

Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation). We report a case of a patient with the complete form of the disease, and with a unique appearance of the hair shaft and eyelashes. The authors propose a possible mechanism to justify the abnormalities observed in the patient's hair shafts regarding the metabolism of prostaglandins and its relationship with the hair follicle physiological cycle.

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