Open AccessHodgkin′s lymphoma presenting as alopecia
Author(s) -
Sunny Garg,
Sourav Mishra,
Ravi Tondon,
Kamlakar Tripathi
Publication year - 2012
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/0974-7753.100085
Subject(s) - medicine , hair loss , dermatology , malignancy , scalp , lymphoma , groin , axilla , disease , itching , infiltration (hvac) , pathology , surgery , breast cancer , cancer , physics , thermodynamics
Alopecia is a rare manifestation of Hodgkin's disease. It may be due to follicular destruction due to direct infiltration by the disease, or it may be a secondary or paraneoplastic manifestation. In this patient, hair loss, diffuse yperpigmentation, and generalized itching preceded other manifestations of the disease. The pattern of hair loss was diffuse and generalized in nature involving scalp, eyebrows, axilla, and groin. Subsequently, the patient was diagnosed to be a case of Hodgkin's lymphoma, based on clinical and histopathological features. Earlier reports on alopecia accompanying Hodgkin's disease have also been discussed. This case highlights the importance of keeping a high suspicion of an underlying malignancy in patients presenting with such cutaneous manifestations.