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Carcinoid tumors: Challenges and considerations during anesthetic management
Author(s) -
Sukhminder Jit Singh Bajwa,
Aparajita Panda,
Gurpreet Kaur
Publication year - 2015
Publication title -
journal of the scientific society
Language(s) - English
Resource type - Journals
eISSN - 2278-7127
pISSN - 0974-5009
DOI - 10.4103/0974-5009.165537
Subject(s) - medicine , octreotide , enterochromaffin cell , carcinoid syndrome , carcinoid tumors , somatostatin , complication , neuroendocrine tumors , surgery , receptor , serotonin
Carcinoid tumors are rare, slow-growing neoplasms of neuroendocrine tissues from enterochromaffin or kulchitsky cells, which have the potential to metastasize. The mediators released from these tumors when bypass the hepatic metabolism, can lead to the possible development of carcinoid syndrome. This is a life-threatening complication, which can lead to profound hemodynamic instability, especially in a peri-operative period, when the patient is exposed to various types of noxious stimuli. Off late, use of octreotide, a synthetic analog of somatostatin, has significantly reduced the peri-operative morbidity and mortality. The current review discusses the various anesthetic challenges and considerations during peri-operative management of carcinoid tumors

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