Open AccessSerum cholesterol and depression: A puzzle never finished
Author(s) -
Satish Kumar Budania,
Monika Rathi,
Shalini Singh,
Sher Singh Yadav
Publication year - 2015
Publication title -
journal of the scientific society
Language(s) - English
Resource type - Journals
eISSN - 2278-7127
pISSN - 0974-5009
DOI - 10.4103/0974-5009.157023
Subject(s) - medicine , depression (economics) , folic acid , etiology , serum cholesterol , sadness , antidepressant , cholesterol , psychiatry , anger , hippocampus , economics , macroeconomics
Depression is a state of sadness, hopelessness, and discouragement. Various studies have been conducted to uncover the etiological factors involved in depression. Serum folic acid is one such factor. Many researchers have reported an inverse association between serum folic acid and depression. We did an extensive computerized database searches on PubMed, Medline, and EBSCO and found that low serum folic acid are associated with depression, not only in adults, but also in elderly and diabetic patients. Further augmentation of folic acid with antidepressant treatment also improves the treatment outcome in depressed patients. Hence, considering the high benefits to the adverse effects ratio of serum folic acid, its supplementation should be done in "at risk" population whenever possible