Open AccessAnencephaly: A pathological study of 41 cases
Author(s) -
C Panduranga,
Ranjit Kangle,
Vijayalaxmi V Suranagi,
Ganga S Pilli,
Pradeep S Patil
Publication year - 2012
Publication title -
journal of the scientific society
Language(s) - English
Resource type - Journals
eISSN - 2278-7127
pISSN - 0974-5009
DOI - 10.4103/0974-5009.101852
Subject(s) - anencephaly , medicine , pathological , neural tube , spina bifida , pediatrics , obstetrics , pathology , biology , embryo , microbiology and biotechnology
Background : Anencephaly is a lethal neural tube defect which is due to the defective closure of rostral pore of neural tube. In more than 50% of cases it is associated with other systemic anomalies. Hence this study was undertaken to assess pathological parameters associated with anencephaly in particular attention to associated systemic anomalies. Materials and Methods: It is a study on 41 anencephaly fetuses conducted in the Department of Pathology. The period of study is from January 2001 to December 2011. Results: Out of 41 cases, 30 (73%) cases showed presence of systemic anomalies, 48.5% of the cases were observed in primigravida. Most common associated anomaly was spina bifida followed by gastrointestinal anomalies. Conclusion: Pathological examination of the abortus is essential to document the associated anomalies