Open AccessAntibiotic resistance pattern of Pseudomonas aureuginosa isolated from healthcare associated infections at a tertiary care hospital
Author(s) -
BV Ramana,
Abhijit Chaudhury
Publication year - 2012
Publication title -
journal of the scientific society
Language(s) - English
Resource type - Journals
eISSN - 2278-7127
pISSN - 0974-5009
DOI - 10.4103/0974-5009.101850
Subject(s) - amikacin , medicine , piperacillin , cefotaxime , cefoperazone , imipenem , ciprofloxacin , pseudomonas aeruginosa , antibiotic resistance , ceftazidime , antibiotics , microbiology and biotechnology , intensive care medicine , biology , bacteria , genetics
Objectives: The present study was undertaken to assess the antibiotic susceptibility patterns of Pseudomonas aeruginosa isolated from healthcare associated infections at a tertiary care hospital. Due to significant changes in microbial genetic ecology, as a result of indiscriminate use of anti-microbials, the spread of anti-microbial resistance is now a global problem. Materials and Methods: A total of 290 Pseudomonas aeruginosa isolates from various clinical samples like urinary catheters, tips of endotracheal tube, and central venous catheter were tested for antibiotic sensitivity pattern using disk diffusion method as per Clinical and Laboratory Standards Institute guidelines. Results: The highest number of Pseudomonas infections was found in urinary catheters, followed by endotracheal tips and central venous catheters. Maximum resistance was seen to cefotaxime and gentamycin (40%) followed by ciprofloxacin (39%), amikacin (26%), cefoperazone- sulbactum (22%), piperacillin-tazobactum (16%), and imipenem (14%). Conclusion: Over all we have observed that there is increased antibiotic resistance which may be due to the selective pressure from the use of anti-microbial agents is a major determinant for the emergence of resistance strains. Antimicrobial surveillance should be done periodically to monitor the current susceptibility patterns in local hospitals