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Salmonella typhimurium infection in total knee arthroplasty: A case report with review of literature
Author(s) -
Sujeesh Sebastian,
Benu Dhawan,
Rajesh Malhotra,
Deepak Gautam,
Arti Kapil
Publication year - 2017
Publication title -
journal of laboratory physicians
Language(s) - English
Resource type - Journals
eISSN - 0974-7826
pISSN - 0974-2727
DOI - 10.4103/0974-2727.208254
Subject(s) - medicine , salmonella enterica , salmonella , ciprofloxacin , septic arthritis , debridement (dental) , human immunodeficiency virus (hiv) , serotype , salmonella infection , arthritis , surgery , arthroplasty , prosthesis , immunology , microbiology and biotechnology , antibiotics , biology , bacteria , genetics
Salmonella enterica serotype Typhimurium is a rare cause of prosthetic joint infection (PJI). The recognized predisposing risk factors for Salmonella septic arthritis include diabetes mellitus, renal failure, human immunodeficiency virus infection and chronic corticosteroid use. We describe a case of PJI of the knee in a 74-year-old lady who was on antitubercular treatment. The patient presented with discharging sinus and raised inflammatory markers. She was successfully treated by the removal of prosthesis and debridement followed by ciprofloxacin therapy for 6 weeks. This case report highlights the potential virulence of Salmonella in immunocompromised patient with a joint prosthesis. Continuous monitoring and close collaboration of microbiologists and orthopedicians helped obtain the resolution of infection in our patient.

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