Open AccessPeriampullary Adenocarcinoid: Diagnostic Dilemma
Author(s) -
Rashmi Krishnappa,
Sudha Horakerappa Metikurke,
H Sridhar,
Rudresh Hosakote,
Nagesh Kumar Talkad Chandrashekar
Publication year - 2013
Publication title -
journal of laboratory physicians
Language(s) - English
Resource type - Journals
eISSN - 0974-7826
pISSN - 0974-2727
DOI - 10.4103/0974-2727.119875
Subject(s) - duodenum , medicine , obstructive jaundice , pancreas , general surgery , biopsy , gastroenterology , pathology
The growth in periampullary region needs proper evaluation as they can arise from duodenum, pancreas and extra hepatic biliary tree. We have reported a case of adenocarcinoid of duodenum presenting as periampullary growth with obstructive jaundice. Histologically, tumor displayed biphasic pattern, i.e. tubuloglandular architecture with admixed sheets of neuroendocrine cells without pancreas and extra hepatic biliary tree involvement. The adenocarcinoids are of great diagnostic challenges for the pathologist interpreting endoscopic biopsy for the frequent misinterpretation as negative due to their submucosal location or as adenocarcinomas due to tubulo-glandular architecture.