Open AccessInsulin treatment before resuscitation following hemorrhagic shock improves cardiac contractility and protects the myocardium in the isolated rat heart
Author(s) -
Mona Soliman
Publication year - 2015
Publication title -
journal of emergencies, trauma and shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 29
eISSN - 0974-519X
pISSN - 0974-2700
DOI - 10.4103/0974-2700.160714
Subject(s) - resuscitation , medicine , contractility , insulin , cardioprotection , shock (circulatory) , inotrope , cardiology , anesthesia , blood pressure , myocardial infarction
Insulin has been shown to exert positive inotropic effects in several in vivo ex vivo models and in human hearts. Resuscitation following hemorrhagic shock results in myocardial contractile dysfunction. However, the optimal timing for treatment with insulin for the cardioprotection effects is unclear.