Open AccessGoal-directed diuresis: A case - control study of continuous furosemide infusion in critically ill trauma patients
Author(s) -
D. Dante Yeh,
Gwendolyn M. van der Wilden,
Catrina Cropano,
Yuchiao Chang,
David R. King,
Marc de Moya,
Peter J. Fagenholz,
Haytham Kaafarani,
Jarone Lee,
George C. Velmahos
Publication year - 2015
Publication title -
journal of emergencies, trauma and shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 29
eISSN - 0974-519X
pISSN - 0974-2700
DOI - 10.4103/0974-2700.150395
Subject(s) - medicine , furosemide , diuresis , hypokalemia , intensive care unit , renal function , anesthesia , creatinine , acute kidney injury , diuretic
Excessive crystalloid administration is common and associated with negative outcomes in critically ill trauma patients. Continuous furosemide infusion (CFI) to remove excessive fluid has not been previously described in this population. We hypothesized that a goal-directed CFI is more effective for fluid removal than intermittent bolus injection (IBI) diuresis without excess incidence of hypokalemia or renal failure.