Open AccessUse of recombinant factor VIIa (rFVIIa) as pre-hospital treatment in a swine model of fluid percussion traumatic brain injury
Author(s) -
Bobby Kim,
Ashraful Haque,
Françoise Arnaud,
Kohsuke Teranishi,
Thomas Steinbach,
Charles R. Auker,
Richard M. McCarron,
Daniel Freilich,
Anke Scultetus
Publication year - 2014
Publication title -
journal of emergencies, trauma and shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 29
eISSN - 0974-519X
pISSN - 0974-2700
DOI - 10.4103/0974-2700.130880
Subject(s) - medicine , neurointensive care , traumatic brain injury , anesthesia , subarachnoid hemorrhage , coagulopathy , bolus (digestion) , propofol , subdural hemorrhage , surgery , hematoma , psychiatry
Recombinant factor VIIa (rFVIIa) has been used as an adjunctive therapy for acute post-traumatic hemorrhage and reversal of iatrogenic coagulopathy in trauma patients in the hospital setting. However, investigations regarding its potential use in pre-hospital management of traumatic brain injury (TBI) have not been conducted extensively.