Open AccessThe role of allopurinol′s timing in the ischemia reperfusion injury of small intestine
Author(s) -
Konstantinos Sapalidis,
Theodossis S. Papavramidis,
Eleftherios Gialamas,
Nikolaos Deligiannidis,
Valentini Tzioufa,
Spiros Papavramidis
Publication year - 2013
Publication title -
journal of emergencies, trauma and shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 29
eISSN - 0974-519X
pISSN - 0974-2700
DOI - 10.4103/0974-2700.115346
Subject(s) - allopurinol , neopterin , ischemia , malondialdehyde , xanthine oxidase , medicine , reperfusion injury , superoxide dismutase , small intestine , pharmacology , intestinal mucosa , anesthesia , oxidative stress , chemistry , biochemistry , enzyme
Allopurinol acts protectively in the ischemia reperfusion injury of the small intestine. The aim of this experimental study is to define the ideal time of administration of allopurinol, in experimental models of ischemia/reperfusion.