Open AccessManagement of infantile hemangiomas: Current trends
Author(s) -
Gomathy Sethuraman,
Vamsi K Yenamandra,
Vishal Gupta
Publication year - 2014
Publication title -
journal of cutaneous and aesthetic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.44
H-Index - 13
eISSN - 0974-5157
pISSN - 0974-2077
DOI - 10.4103/0974-2077.138324
Subject(s) - medicine , infantile hemangioma , involution (esoterism) , vincristine , timolol , birthmark , pediatrics , dermatology , hemangioma , surgery , chemotherapy , cyclophosphamide , intraocular pressure , politics , political science , law
Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proportion of cases requiring intervention. These are children with IH in life-threatening locations, local complications like haemorrhage, ulceration and necrosis and functional or cosmetic disfigurements. Systemic corticosteroids have been the first line of treatment for many years. Recently, non-selective beta-blockers, such as oral propranalol and topical timolol, have emerged as promising and safer therapies. Other treatment options include interferon α and vincristine which are reserved for life-threatening haemangiomas that are unresponsive to conventional therapy. This review mainly focuses on the current trends and evidence-based approach in the management of IH.