Open AccessLuteinizing hormone and follicle stimulating hormone synergy: A review of role in controlled ovarian hyper-stimulation
Author(s) -
Gottumukkala Achyuta Rama Raju,
Rahul B. Chavan,
Mamata Deenadayal,
Devika Gunasheela,
Rohit Gutgutia,
Geetha Haripriya,
Mirudhubashini Govindarajan,
Nandish V. Patel,
Ameet Patki
Publication year - 2013
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/0974-1208.126285
Subject(s) - luteinizing hormone , ovulation , stimulation , follicle stimulating hormone , endocrinology , medicine , hormone , follicular phase , hypogonadotropic hypogonadism , population , gonadotropic cell , environmental health
Luteinizing hormone (LH) in synergy with follicle stimulating hormone (FSH) stimulates normal follicular growth and ovulation. FSH is frequently used in assisted reproductive technology (ART). Recent studies have facilitated better understanding on the complementary role of the LH to FSH in regulation of the follicle; however, role of LH in stimulation of follicle, optimal dosage of LH in stimulation and its importance in advanced aged patients has been a topic of discussion among medical fraternity. Though the administration of exogenous LH with FSH is obligatory for controlled ovarian stimulation in patients with hypogonadotropic hypogonadism, there is still a paucity of information of its usage in other patient population. In this review we looked in to the multiple roles that LH plays complementary to FSH to better understand the LH requirement in patients undergoing ART.