Open AccessSerological study on parvovirus B19 infection in multitransfused thalassemia major patients and its transmission through donor units
Author(s) -
Janak Kishore,
Mohit Srivastava,
Nikumani Choudhury
Publication year - 2011
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.83239
Subject(s) - medicine , thalassemia , serology , antibody , parvovirus , hbsag , immunology , blood transfusion , virology , beta thalassemia , virus , transmission (telecommunications) , immunoglobulin m , hepatitis b virus , immunoglobulin g , electrical engineering , engineering
Human parvovirus B19 (B19) virus is a newly recognized agent for transfusion transmitted diseases. Beta-thalassemia major patients receive a hypertransfusion regimen, hence, are prone to acquire B19 infection; moreover, B19 escapes viral inactivation methods and donor units are not tested for B19, but there are just a couple of studies globally and none from the Asian continent. Hence, a study was designed to find the frequency of B19 infection and its transmission in multitransfused thalassemia patients.