Open AccessProbing rate of YMDD motif mutant in lamivudine treatment of Iranian patients with chronic hepatitis B virus infection
Author(s) -
A Pourazar,
MehrnazShanehsaz Zadeh,
Nahid Tajedin,
Freshte Ghandehari
Publication year - 2011
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.75982
Subject(s) - medicine , lamivudine , virology , chronic hepatitis , virus , hepatitis b virus , mutant , gene , genetics , biology
Lamivudine is an analog nucleoside used for the treatment of chronic hepatitis B virus (CHV) infection. Studies showed that prolonged therapy could induce lamivudine resistance hepatitis B virus (HBV) variants (YMDD motif). In this study, the rate of YMDD motif mutants is determined in lamivudine-treated CHV patients in Iran.
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