Open AccessProbing rate of YMDD motif mutant in lamivudine treatment of Iranian patients with chronic hepatitis B virus infection
Author(s) -
Fereshte Ghandehari,
Abasali Pourazar,
Mehrnaz Shanehsaz Zadeh,
Nahid Tajedin
Publication year - 2011
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.75982
Subject(s) - lamivudine , medicine , hbsag , hbeag , gastroenterology , virology , hepatitis b virus , virus , chronic hepatitis
Lamivudine is an analog nucleoside used for the treatment of chronic hepatitis B virus (CHV) infection. Studies showed that prolonged therapy could induce lamivudine resistance hepatitis B virus (HBV) variants (YMDD motif). In this study, the rate of YMDD motif mutants is determined in lamivudine-treated CHV patients in Iran.