Open AccessTransfusion-transmitted parasitic infections
Author(s) -
Gagandeep Singh,
Rakesh Sehgal
Publication year - 2010
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.67018
Subject(s) - medicine , malaria , babesiosis , intensive care medicine , infectious disease (medical specialty) , serology , immunology , brucellosis , transmission (telecommunications) , disease , parasitic infection , virology , pathology , antibody , electrical engineering , engineering
The transmission of parasitic organisms through transfusion is relatively rare. Of the major transfusion-transmitted diseases, malaria is a major cause of TTIP in tropical countries whereas babesiosis and Chagas' disease pose the greatest threat to donors in the USA In both cases, this is due to the increased number of potentially infected donors. There are no reliable serologic tests available to screen donors for any of these organisms and the focus for prevention remains on adherence to donor screening guidelines that address travel history and previous infection with the etiologic agent. One goal is the development of tests that are able to screen for and identify donors potentially infectious for parasitic infections without causing the deferral of a large number of non-infectious donors or significantly increasing costs. Ideally, methods to inactivate the infectious organism will provide an element of added safety to the blood supply.