Open AccessRh antigen expression during erythropoeisis: Comparison of cord and adult derived CD34 + cells
Author(s) -
Namita Gupta,
Lakshmi Kiran Chelluri,
K.S. Ratnakar,
K. Ravindhranath,
Vasantha Adavi
Publication year - 2008
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.42694
Subject(s) - cord blood , antigen , progenitor cell , flow cytometry , cd34 , umbilical cord , andrology , microbiology and biotechnology , medicine , immunology , stem cell , biology
Concentrations of O(2) and CO(2) in the fetal circulation differ to that in maternal blood. Previous studies done in algae demonstrate the functional role of Rh antigen as CO(2) transporter. As a preliminary study, it was the aim of this project to compare the expression of Rh polypeptides on cord and adult red blood cell progenitors during ex vivo proliferation and differentiation of CD34(+) cells during erythropoeisis.