Open AccessImpact of antigenic exposures and role of molecular blood grouping in enhancing transfusion safety in chronically transfused thalassemics
Author(s) -
Raj Nath Makroo,
Soma Agrawal,
Aakanksha Bhatia,
Mohit Chowdhry,
Uday Kumar Thakur
Publication year - 2016
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.187942
Subject(s) - medicine , genotyping , antigen , blood transfusion , thalassemia , abo blood group system , immunology , serology , antibody , genotype , gene , biology , genetics
Red cell alloimmunization is an acknowledged complication of blood transfusion. Current transfusion practices for thalassemia do not cater to this risk. Serological phenotyping is usually not reliable in these cases unless performed before the first transfusion. Under such circumstances, molecular blood grouping is an effective alternative.