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Transfusion reaction in a case with the rare Bombay blood group
Author(s) -
Hayedeh Javadzadeh Shahshahani,
Mohamad Reza Vahidfar,
Seyed Ali Khodaie
Publication year - 2013
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.106754
Subject(s) - medicine , abo blood group system , blood typing , transfusion reaction , blood transfusion , incidence (geometry) , blood units , blood grouping , blood type (non human) , transfusion medicine , surgery , immunology , physics , optics
Bombay phenotype is extremely rare in Caucasian with an incidence of 1 in 250,000. When individuals with the Bombay phenotype need blood transfusion, they can receive only autologous blood or blood from another Bombay blood group. Transfusing blood group O red cells to them can cause a fatal hemolytic transfusion reaction. In this study, we report a case with the rare Bombay blood group that was misdiagnosed as the O blood group and developed a hemolytic transfusion reaction. This highlights the importance of both forward and reverse typing in ABO blood grouping and standard cross-matching and performing standard pretransfusion laboratory tests in hospital blood banks.

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