Open AccessHemolytic disease of the fetus and newborn caused by anti-E
Author(s) -
Adiyyatu Sa'idu Usman,
Rapiaah Mustaffa,
Nor Azam Ramli,
Sirajo A Diggi
Publication year - 2013
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.106750
Subject(s) - medicine , fetus , hemolysis , hemolytic disease of the newborn (abo) , antibody , hemolytic anemia , anemia , antigen , immunology , disease , pregnancy , immune system , rh isoimmunization , exchange transfusion , rh blood group system , genetics , biology
Maternal allo-antibody production is stimulated when fetal red blood cells are positive for an antigen absent on the mother's red cells. The maternal IgG antibodies produced will pass through the placenta and attack fetal red cells carrying the corresponding antigen. Allo-immune hemolytic disease of the fetus and newborn caused by anti-E rarely occurs.