Open AccessPrimary squamous cell carcinoma of the breast: Case report and management decisions
Author(s) -
Nidhi Gupta,
Rajesh Vashisht,
Vinod Nimbran,
Rakesh Gupta,
Neerja Dhingra,
Anjali Bhutani
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.99006
Subject(s) - medicine , oncology , breast carcinoma , lymph node , chemotherapy , carcinoma , basal cell , primary tumor , breast cancer , cancer , metastasis
Though breast carcinoma is one of the most common malignancies worldwide, adequate knowledge of this disease is still very poor. Pure primary squamous cell carcinoma of breast is one such mystery, which is encountered very rarely. Its clinical behavior should not be correlated with the standard infiltrating duct carcinoma of breast. It follows an atypical presentation in terms of tumor size, lymph node and systemic spread. It is generally a triple negative tumor with an aggressive behavior and resistance to standard chemotherapeutic regimens. Management decisions need to be individualized with emphasis toward platinum-based chemotherapy and targeted therapy.