Open AccessAssessment of the redox profile and oxidative DNA damage (8-OHdG) in squamous cell carcinoma of head and neck
Author(s) -
Anil Kumar,
M. C. Pant,
Hridaya Shanker Singh,
Shashi Khandelwal
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.98980
Subject(s) - oxidative stress , reactive oxygen species , dna damage , antioxidant , glutathione , biomarker , radical , chemistry , oxidative phosphorylation , reactive nitrogen species , head and neck cancer , head and neck squamous cell carcinoma , cancer , medicine , biochemistry , oncology , cancer research , dna , enzyme
In developing countries especially in south Asia, there are growing habits of consumption of tobacco and its products in various forms. These are known to generate a strong free radical environment and when the free radicals overwhelm the antioxidant system, they may lead to degeneration of cellular components and mutations.