Open AccessSquamotous-type sarcomatoid carcinoma of the lung with rhabdomyosarcomatous components
Author(s) -
Figen Türk,
Gökhan Yüncü,
Ferda Bir,
Gökhan Öztürk,
Yasin Ekıncı
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.95199
Subject(s) - carcinosarcoma , sarcomatoid carcinoma , rhabdomyosarcoma , pathology , fibrosarcoma , squamous cell carcinoma of the lung , lung , sarcoma , medicine , carcinoma , spindle cell sarcoma , squamous carcinoma , basal cell , spindle cell carcinoma , adenosquamous carcinoma , asbestosis , adenocarcinoma , cancer
Lung carcinosarcoma is an infrequently biphasic tumor composed of carcinomatous and sarcomatous components. It is divided into endobronchial (squamous-type) and peripheral (glandular type) categories. The carcinomatous component is usually a squamous carcinoma, and the sarcomatous component usually resembles a fibrosarcoma or a malignant fibrous histiocytoma. The presence of rhabdomyoblastic differentiation in such neoplasms is exceedingly rare. There are strong associations with smoking and asbestosis. In this study, we describe a unique case of a 43-year-old man with a 75 packet/year smoking history in whom a rare mixed malignant tumor of the lung was diagnosed and treated by left pneumonectomy. Histological examination of the resected specimen showed squamous cell carcinoma and rhabdomyosarcoma components. Although rare, the association of a sarcomatoid carcinoma of the lung with squamous cell carcinoma and rhabdomyosarcomatous component is possible and should be kept in mind when dealing with these unusual tumors.