Open AccessA fatal case of mesenchymal chondrosarcoma of the mandible
Author(s) -
Arvind Krishnamurthy,
Anitha Vaidhyanathan,
Satish Srinivas,
Urmila Majhi
Publication year - 2011
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.82919
Subject(s) - cd99 , mesenchymal chondrosarcoma , vimentin , maxilla , mandible (arthropod mouthpart) , mesenchymal stem cell , chondrosarcoma , pathology , immunohistochemistry , medicine , neoplasm , anatomy , biology , botany , genus
A 34-year-old man presented with an expansile, erosive tumor involving the left side of the mandible, with secondary invasion into the maxilla, measuring 13 Χ 7 cm. Microscopic analysis revealed a malignant small round cell neoplasm with focal cartilaginous differentiation. Immunohistochemical analysis revealed positivity for vimentin, NSE and CD99 with primitive small round cells, and S100 positivity with neoplastic chondrocytes. To the best of our knowledge, this is perhaps the largest reported case of mesenchymal chondrosarcoma of the maxillofacial region. Diagnosed as inoperable, he was treated with radiation and chemotherapy only to die within a few months.