Open AccessPrimary bone lymphoma: A report of two cases and review of the literature
Author(s) -
Tejinder Singh,
C T Satheesh,
K C Lakshmaiah,
T. M. Suresh,
Govind Babu,
Lokanatha Dasappa,
Linu Abraham Jacob,
Rajashekar Halkud
Publication year - 2010
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.73366
Subject(s) - medicine , lymphoma , radiation therapy , pathological , spinal cord compression , presentation (obstetrics) , primary bone , disease , chemotherapy , radiology , pathology , surgery , spinal cord , psychiatry
Primary bone lymphoma (PBL) is an uncommon tumor accounting for approximately 4-5% of extra nodal lymphoma and less than 1% of all non-Hodgkin's lymphoma. Disease may be complicated at presentation by pathological fracture or spinal cord compression. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL. Owing to its rarity, only a few retrospective studies have been published addressing the prognosis and treatment of primary bone lymphoma. In this paper, we report our experience with two cases of PBL treated with chemotherapy and radiotherapy and review literature to elucidate the optimal treatment of primary bone lymphoma.