Open AccessUnresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: A case report with review of literature
Author(s) -
Nikhil Joshi,
K.P. Haresh,
Prasenjit Das,
Rajender Kumar,
R Prabhakar,
Daya Nand Sharma,
Puthiyeduthu Heera,
Pramod Kumar Julka,
Goura Kishor Rath
Publication year - 2010
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.73341
Subject(s) - medicine , carboplatin , chemoradiotherapy , adenoid cystic carcinoma , radiation therapy , pathology , carcinoma , basal cell , pathological , chemotherapy , oncology , cisplatin
Basaloid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma of the trachea. We describe the case of an unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy up to a dose of 60 Gy in 33 fractions with weekly paclitaxel and carboplatin. The pathological recognition of basaloid squamous cell carcinoma and its distinction from adenoid cystic carcinoma of the trachea is important for its management. Combining systemic chemotherapy with locoregional radiation is a logical approach to treatment, especially for the basaloid squamous cell carcinoma of the trachea, given its tendency to metastasize early after definitive therapy.