Open AccessLate recurrence in orbital rhabdomyosarcoma: Complete remission after multimodality management
Author(s) -
Arun Warrier,
Sanju Syriac,
Krishnakumar Rathnam
Publication year - 2010
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.73326
Subject(s) - medicine , radiation therapy , complete remission , pathological , rhabdomyosarcoma , surgery , chemotherapy , immunohistochemistry , radiology , pathology , sarcoma
A case of orbital rhabdomyosarcoma had a localised recurrence 13 years after being treated with chemo radiotherapy. Late recurrences are rare in orbital RMS. Only two cases have been reported to have recurred after five years of follow up. Pathological similarity of both the lesions and occurrence outside the irradiated field excluded a radiation-induced second neoplasm. Immunohistochemistry staining with p 53 was positive. Patient had good response to chemotherapy and radiotherapy. Surgical resection of residue showed complete necrosis. Retreatment with combined modality therapy resulted in complete remission and the patient is on follow up.