Diffuse large B-cell lymphoma of the uterine cervix: A rare case managed novelly | Zendy

MS Vidyasagar | Zendy; Gunjan Baijal | Zendy; BM Vadiraja | Zendy; DonaldJ Fernandes | Zendy

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Diffuse large B-cell lymphoma of the uterine cervix: A rare case managed novelly

Author(s) -

MS Vidyasagar,

Gunjan Baijal,

BM Vadiraja,

DonaldJ Fernandes

Publication year - 2009

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.52784

Subject(s) - medicine , rituximab , cervix , vincristine , lymphoma , prednisolone , cyclophosphamide , biopsy , radiation therapy , external beam radiotherapy , radiology , cd20 , surgery , chemotherapy , cancer , brachytherapy

Non-Hodgkin's lymphoma (NHL) of the uterine cervix is exceedingly rare. The management of the disease is not standardized. A 44-year-old lady presented with a history of bleeding pervaginum and a foul-smelling discharge of 2 months' duration. A 7 x 7 growth was seen in the cervix. A biopsy revealed it to be a CD20-positive diffuse large B-cell (DLBCL)-type NHL. She was diagnosed as stage IE after staging work-up, and managed with three courses of rituximab, cyclophosphamide, vincristine, adriamycin, and prednisolone followed by external beam radiotherapy (46 Gy in 23 fractions) by 3D conformal technique. She attained a complete response, and has been in remission for 1 year 3 months.

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