Open AccessDiffuse large B-cell lymphoma of the uterine cervix: A rare case managed novelly
Author(s) -
Gunjan Baijal,
B M Vadiraja,
Donald J Fernandes,
M S Vidyasagar
Publication year - 2009
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.52784
Subject(s) - medicine , rituximab , cervix , vincristine , lymphoma , prednisolone , cyclophosphamide , biopsy , radiation therapy , external beam radiotherapy , radiology , cd20 , surgery , chemotherapy , cancer , brachytherapy
Non-Hodgkin's lymphoma (NHL) of the uterine cervix is exceedingly rare. The management of the disease is not standardized. A 44-year-old lady presented with a history of bleeding pervaginum and a foul-smelling discharge of 2 months' duration. A 7 x 7 growth was seen in the cervix. A biopsy revealed it to be a CD20-positive diffuse large B-cell (DLBCL)-type NHL. She was diagnosed as stage IE after staging work-up, and managed with three courses of rituximab, cyclophosphamide, vincristine, adriamycin, and prednisolone followed by external beam radiotherapy (46 Gy in 23 fractions) by 3D conformal technique. She attained a complete response, and has been in remission for 1 year 3 months.