Open AccessTransient asymptomatic bradycardia in patients on infusional 5-fluorouracil
Author(s) -
Kaustav Talapatra,
Idhuyya Joseph Rajesh,
B Rajesh,
Selvamani Backianathan,
Stanley John
Publication year - 2007
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.37412
Subject(s) - bradycardia , asymptomatic , medicine , fluorouracil , cardiotoxicity , anesthesia , incidence (geometry) , electrocardiography , transient (computer programming) , cardiology , chemotherapy , heart rate , physics , computer science , blood pressure , optics , operating system
The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent. Although various other cardiac events have been reported in literature, a series of patients having transient asymptomatic bradycardia has not been reported in the literature as yet. We report such a series of patients who had transient asymptomatic bradycardia after being treated with continuous infusion 5-FU. We plan to do a Holter study during the period of bradycardia in subsequent patients and this may throw more light on the issue.