Serum total glutathione-s-transferase levels in oral cancer | Zendy

Krishnananda Prabhu | Zendy; GopalakrishnaP Bhat | Zendy

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Serum total glutathione-s-transferase levels in oral cancer

Author(s) -

Krishnananda Prabhu,

GopalakrishnaP Bhat

Publication year - 2007

Publication title -

journal of cancer research and therapeutics

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.37411

Subject(s) - glutathione , glutathione s transferase , cancer , stage (stratigraphy) , medicine , biopsy , oncology , gastroenterology , biology , enzyme , biochemistry , paleontology

We conducted a study wherein serum total glutathione-s-transferase levels were measured in patients (n = 27) with various stages of biopsy proven oral cancer (squamous cell carcinoma) and age and sex matched healthy human volunteers (n=10). In all patients with oral cancer, serum total glutathione-s-transferase was measured before the onset of treatment. There was a significant increase in serum total glutathione-s-transferase levels in patients with stage IV oral cancer as compared to stage II (P = 0.001) and stage III (P = 0.002) oral cancer. This shows that alterations in serum total Glutathione-s-transferase levels may have a role in cancer progression.

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