The more potential performance of nidogen 2 methylation by tissue or plasma DNA over brichoalveolar lavage DNA in diagnosis of nonsmall cell lung cancer | Zendy

Feng Xu | Zendy; Xiaoyong Xie | Zendy; Baoshi Zheng | Zendy; Chaoyang Peng | Zendy; HuaFu Zhou | Zendy; Qin Jia-jin | Zendy

Open Access

The more potential performance of nidogen 2 methylation by tissue or plasma DNA over brichoalveolar lavage DNA in diagnosis of nonsmall cell lung cancer

Author(s) -

Feng Xu,

Xiaoyong Xie,

Baoshi Zheng,

Chaoyang Peng,

HuaFu Zhou,

Qin Jia-jin

Publication year - 2018

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.235352

Subject(s) - lung cancer , dna methylation , biomarker , methylation , carcinogenesis , bronchoalveolar lavage , medicine , polymerase chain reaction , oncology , population , pathology , lung , cancer , cancer research , biology , gene , gene expression , biochemistry , environmental health

Nonsmall cell lung cancer (NSCLC) is one of the leading incidence and mortality of malignant tumors worldwide. While aberrant DNA methylation is a frequent event occurred during NSCLC carcinogenesis and development, therefore holding the potential to predict the process of tumor development. This study aims to explore the feasibility of gene nidogen 2 (NID2) as the diagnostic biomarker for NSCLC.

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