Open AccessThe more potential performance of nidogen 2 methylation by tissue or plasma DNA over brichoalveolar lavage DNA in diagnosis of nonsmall cell lung cancer
Author(s) -
Feng Xu,
Xiaoxue Xie,
Baoshi Zheng,
Chaoyang Peng,
Hua-Fu Zhou,
Junqi Qin
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.235352
Subject(s) - lung cancer , dna methylation , biomarker , methylation , carcinogenesis , bronchoalveolar lavage , medicine , polymerase chain reaction , oncology , population , pathology , lung , cancer , cancer research , biology , gene , gene expression , biochemistry , environmental health
Nonsmall cell lung cancer (NSCLC) is one of the leading incidence and mortality of malignant tumors worldwide. While aberrant DNA methylation is a frequent event occurred during NSCLC carcinogenesis and development, therefore holding the potential to predict the process of tumor development. This study aims to explore the feasibility of gene nidogen 2 (NID2) as the diagnostic biomarker for NSCLC.