The administration of peroxisome proliferator-activated receptors α/γ agonist TZD18 inhibits cell growth and induces apoptosis in human gastric cancer cell lines | Zendy

Yuhong Ma | Zendy; Bin Wang | Zendy; Ling Li | Zendy; Fang Wang | Zendy; Xichao Xia | Zendy

Open Access

The administration of peroxisome proliferator-activated receptors α/γ agonist TZD18 inhibits cell growth and induces apoptosis in human gastric cancer cell lines

Author(s) -

Yuhong Ma,

Bin Wang,

Ling Li,

Fang Wang,

Xichao Xia

Publication year - 2017

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.208753

Subject(s) - apoptosis , cytochrome c , cell growth , microbiology and biotechnology , biology , cell culture , flow cytometry , receptor , cancer cell , peroxisome proliferator activated receptor , biochemistry , cancer , genetics

This study is to investigate the effects of a novel peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist TZD18 on cell growth, apoptosis, caspase activity, mitochondrial membrane potential, cytochrome c release, and apoptotic-related protein expression in MKN-45 cells.

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