Nuclear forkhead box O3a accumulation contributing to the proliferative suppression in liver cancer cells by PI3K/Akt signaling pathway | Zendy

Yibin Hou | Zendy; Ge Sun | Zendy; Jiang Xu | Zendy; Zhongsheng Zhu | Zendy; Jijin Yang | Zendy

Open Access

Nuclear forkhead box O3a accumulation contributing to the proliferative suppression in liver cancer cells by PI3K/Akt signaling pathway

Author(s) -

Yibin Hou,

Ge Sun,

Jiang Xu,

Zhongsheng Zhu,

Jijin Yang

Publication year - 2017

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.204891

Subject(s) - pi3k/akt/mtor pathway , protein kinase b , cancer research , mtt assay , cell growth , chemistry , liver cancer , viability assay , oncogene , cell , signal transduction , microbiology and biotechnology , biology , cell cycle , biochemistry , hepatocellular carcinoma

Serine/threonine kinase is originally identified as an oncogene and the forkhead box transcription factor forkhead box O3a (Foxo3a) has been found to be decreased in various human cancers. In the present study, we explored the expression of Akt and FOXO3a in liver cancer cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research