To evaluate immunoreactivity of cyclooxygenase-2 in cases of endometrial carcinoma and correlate it with expression of p53 and vascular endothelial growth factor | Zendy

B. S. Sunita | Zendy; Arijit Sen | Zendy; Virender Suhag | Zendy

Open Access

To evaluate immunoreactivity of cyclooxygenase-2 in cases of endometrial carcinoma and correlate it with expression of p53 and vascular endothelial growth factor

Author(s) -

B. S. Sunita,

Arijit Sen,

Virender Suhag

Publication year - 2017

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.202890

Subject(s) - endometrial cancer , medicine , vascular endothelial growth factor , stage (stratigraphy) , carcinoma , carcinogenesis , cyclooxygenase , immunohistochemistry , proportional hazards model , endometrium , angiogenesis , oncology , cancer , pathology , vegf receptors , biology , enzyme , paleontology , biochemistry

Increased levels of prostaglandins have been detected in cancers of several anatomic sites, including those of endometrium. Several studies have shown that cyclooxygenase-2 (COX-2) expression is aberrantly increased in various human epithelial cancers, and cellular up-regulation of COX-2 may be a common mechanism in epithelial carcinogenesis.

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