Open AccessThe effects of thymoquinone and genistein treatment on telomerase activity, apoptosis, angiogenesis, and survival in thyroid cancer cell lines
Author(s) -
Sibel Azizenur Ozturk,
Ebru Alp,
Atiye Seda Yar Sağlam,
Ece Konaç,
Emine Sevda Menevşe
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.202886
Subject(s) - angiogenesis , survivin , telomerase , cancer research , telomerase reverse transcriptase , follicular thyroid cancer , thyroid cancer , pten , thymoquinone , viability assay , cancer , anaplastic thyroid cancer , vascular endothelial growth factor , medicine , biology , apoptosis , pi3k/akt/mtor pathway , papillary thyroid cancer , biochemistry , vegf receptors , gene , antioxidant
Thyroid cancers (TCs) are the most common endocrine malignancies. There were two problems with the current cancer chemotherapy: the ineffectiveness of treatment due to resistance to cancer cell, and the toxic effect on normal cells.