Open AccessCirculating microRNA-21 as a prognostic, biological marker in cholangiocarcinoma
Author(s) -
Chenhai Liu,
Qiang Huang,
Zhongwu Jin,
Fang Xie,
Chenglin Zhu,
Zhen Liu,
Chao Wang
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.193125
Subject(s) - hepatolithiasis , medicine , biomarker , stage (stratigraphy) , gastroenterology , microrna , clinical significance , cancer , tumor marker , oncology , receiver operating characteristic , real time polymerase chain reaction , metastasis , biology , surgery , hepatectomy , paleontology , biochemistry , resection , gene
The prognosis of cholangiocarcinoma (CCA) is generally poor because there is a lack of effective diagnostic tools including laboratory assessments and imageological examination. Therefore, a novel biological marker (biomarker) to effectively diagnose cancer is highly desirable in clinical. Previously, serum microRNAs as biomarkers of cancers have been reported. However, it was still unclear about the clinical significance of serum microRNA-21 (miR-21) expression levels for CCA.