Open AccessDownregulation of DBN1 is related to vincristine resistance in colon cancer cells
Author(s) -
Han Zhou,
Hemei Huang,
Tao Zhang
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.192766
Subject(s) - cell culture , colorectal cancer , western blot , real time polymerase chain reaction , vincristine , downregulation and upregulation , microbiology and biotechnology , drug resistance , cancer research , gene expression , cell , biology , gene , cancer , polymerase chain reaction , chemotherapy , genetics , cyclophosphamide
This study was aimed to investigate the relationship between the expression of drebrin (DBN1) gene and resistance in colon cancer to reveal the mechanism of tumor drug resistance and provide a basis for the reversal of this drug resistance in tumor cells.