Open AccessRole of dalteparin sodium on the growth of cancer cells and tumor-associated angiogenesis in A549 human lung cancer cell line and grafted mouse model
Author(s) -
Rui Yan,
Dongsheng Wang,
Dan-feng Hu,
Lingxia Huang
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.192765
Subject(s) - a549 cell , angiogenesis , cisplatin , intraperitoneal injection , pharmacology , lung cancer , medicine , saline , vascular endothelial growth factor , chemistry , chemotherapy , vegf receptors
To investigate the effects of dalteparin sodium on the expression of vascular endothelial growth factor (VEGF), VEGF receptor (VEGFR), and hypoxia-inducible factor 1α (HIF-1α) in A549 human lung cancer (LC) cell line and a human A549-grafted nude mouse model.