Cytogenetic damage from hyperthermia,6 MV X-rays, and topotecan in glioblastoma spheroids, simultaneously, and separately | Zendy

Ali NeshastehRiz | Zendy; Nazila Eyvazzadeh | Zendy; Aram Rostami | Zendy; Elmira Azzizolahi | Zendy

Open Access

Cytogenetic damage from hyperthermia,6 MV X-rays, and topotecan in glioblastoma spheroids, simultaneously, and separately

Author(s) -

Ali NeshastehRiz,

Nazila Eyvazzadeh,

Aram Rostami,

Elmira Azzizolahi

Publication year - 2018

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.189239

Subject(s) - topotecan , spheroid , radiation therapy , hyperthermia , clonogenic assay , glioma , cancer research , irradiation , nuclear medicine , glioblastoma , medicine , chemotherapy , chemistry , cell , biology , cell culture , physics , nuclear physics , genetics , biochemistry

Glioblastoma multiform (GBM) is one of the most common brain tumors. Surgery, radiation therapy, hyperthermia, and chemotherapy are the most common treatments for brain tumors such as GBM. This study investigated the cytogenetic damage caused by hyperthermia, radiation (6 MV-X-rays), and topotecan in glioma spheroids, simultaneously and separately.

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