Open AccessGene expression analysis of noncoding PCA3 gene in patients with chronic myeloid leukemia
Author(s) -
Elham Sajjadi,
Amir Atashi,
Mona Agha Mohammad Hossein Tajrishi,
Zeinab Saei
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.187348
Subject(s) - pca3 , myeloid leukemia , prostate cancer , gene expression , biology , cancer research , rna , gene , leukemia , cancer , medicine , immunology , genetics
Nowadays, noncoding RNAs are of special significance to scientists. Among RNAs, long noncoding RNAs (lncRNAs) have an important role in gene expression regulation. Recent studies show aberrant lncRNAs expression in different types of cancer including blood malignancies. As such, lncRNAs could be a possible way for diagnosis and treatment of certain cancers. In the current study, the level of PCA3 gene expression in patients with chronic myeloid leukemia (CML) was compared with normal individuals to find out whether the level of PCA3 in CML patients is increased according to our hypothesis.