Open AccessGenetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer
Author(s) -
Muhammed Öz,
Savaş Karakuş,
Malik Ejder Yıldırım,
Binnur Bağcı,
İsmail Sarı,
Gökhan Bağci,
Çağlar Yıldız,
Özlem Bozoklu Akkar,
Ali Çetin,
Ali Yanık
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.187291
Subject(s) - dicer , genotype , single nucleotide polymorphism , snp , genotyping , endometrial cancer , biology , medicine , allele , oncology , lymphovascular invasion , cancer , gastroenterology , genetics , gene , metastasis , rna interference , rna
Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial cancer (EC) has not yet been studied. We aimed to investigate the prognostic role of rs3742330 SNP of Dicer gene in EC patients.