Open AccessLow-grade myofibroblastic sarcoma of the pancreas: A case report and literature review
Author(s) -
Long Peng,
Yi Tu,
Yong Li,
Weidong Xiao
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.183551
Subject(s) - pancreas , splenectomy , asymptomatic , sarcoma , distal pancreatectomy , pancreatectomy , abdominal cavity , abdominal pain , adjuvant therapy , medicine , chemotherapy , pathology , surgery , spleen
Low-grade myofibroblastic sarcoma (LGMS) is a malignant tumor with myofibroblastic differentiation, which frequently occurs in the oral cavity and extremities. Here, we report a case of LGMS of the pancreas in a 44-year-old female presented to our hospital with recurrent upper abdominal pain. Computed tomography revealed a low-density solid tumor at the body of the pancreas. Distal pancreatectomy combined with splenectomy was performed. LGMS of the pancreas was diagnosed by the histological features together with immunohistochemical findings. The patient received adjuvant chemotherapy after surgery and remained asymptomatic for 5 years. Previous studies and our experience suggested that surgical excision with wide margins is the reasonable treatment of LGMS and adjuvant therapy may improve its prognosis.