Open AccessThe expression of insulin receptor substrate 1 and estrogen receptor as prognostic factor on breast cancer patient
Author(s) -
Hyun Goo Kim,
Sang Uk Woo,
Hoon Yub Kim,
Gil Soo Son,
Jae Bok Lee,
Jeong Won Bae,
Ok Hee Woo,
Dae Sik Yang,
Jae Hong Seo,
Ae Ree Kim
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.181180
Subject(s) - breast cancer , estrogen receptor , medicine , oncology , hazard ratio , tissue microarray , cancer , progesterone receptor , immunohistochemistry , univariate analysis , confidence interval , multivariate analysis
Insulin receptor substrate 1 (IRS-1) has been known to be an associated factor with breast cancer progression. However, there has been little study with respect to the relationship between the expression of IRS-1 and breast cancer prognosis in clinical practice. In this study, we evaluated the impact of the estrogen receptor (ER) and IRS-1 on the recurrence and survival of breast cancer patients.