Open AccessA randomized phase III study of hepatic arterial infusion chemotherapy with 5-fluorouracil and subsequent systemic chemotherapy versus systemic chemotherapy alone for colorectal cancer patients with curatively resected liver metastases (Japanese Foundation for Multidisciplinary Treatment of Cancer 32)
Author(s) -
Mitsuo Kusano,
Toru Aoyama,
Koji Okabayashi,
Koichi Hirata,
Y Tsuji,
Shoji Nakamori,
Toshimasa Asahara,
Yasuo Ohashi,
Takaki Yoshikawa,
Junichi Sakamoto,
Koji Oba,
Shigetoyo Saji
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.179188
Subject(s) - medicine , tegafur , chemotherapy , fluorouracil , colorectal cancer , randomized controlled trial , gastroenterology , hazard ratio , hepatic arterial infusion , surgery , cancer , oncology , confidence interval
This randomized phase III trial compared hepatic arterial infusion (HAI) chemotherapy with 5-fluorouracil (5-FU) followed by uracil/tegafur (UFT) and leucovorin (LV) versus UFT/LV alone for patients with curatively resected liver metastases from colorectal cancer (CRC).