Open AccessExpression analysis of human epidermal growth factor receptor type 2 transcripts in breast cancer cohort and its association with clinical features
Author(s) -
Alia Pervez,
Syeda Kiran Riaz,
Azhar Mehmood,
Rakhshanda Rashid,
Muhammad Ehsan Malik
Publication year - 2016
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.176179
Subject(s) - breast cancer , medicine , cohort , oncology , clinical significance , cancer , epidermal growth factor receptor , stage (stratigraphy) , human epidermal growth factor receptor 2 , real time polymerase chain reaction , population , pathology , biology , gene , paleontology , biochemistry , environmental health
Increased expression of human epidermal growth factor receptor type 2 (HER2) is significantly associated with poor prognosis in breast cancer patients. However, data on HER2 at transcript levels in Pakistani mammary tumor affected females is still limited. In the current study, HER2 transcripts were explored in breast cancer cohort and correlated with various clinical parameters.