Open AccessEffects of EF-24, RAD001, and paclitaxel on the expression profiles of apoptotic and anti-apoptotic genes
Author(s) -
Ebru Alp,
Akın Yılmaz,
Hacer İlke Önen,
Emine Sevda Menevşe
Publication year - 2017
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.176172
Subject(s) - apoptosis , paclitaxel , viability assay , gene , gene expression , messenger rna , biology , microbiology and biotechnology , cancer cell , cell , real time polymerase chain reaction , chemistry , cancer research , cancer , biochemistry , genetics
Cancer cells exert differential responses to chemotherapeutics and inhibitors. To the best of our knowledge, a few or no research has been performed until now to determine the effect of EF-24 and RAD001 on MDA-MB-231 breast cancer cells with regard to mRNA expression of apoptotic and anti-apoptotic genes.