Open AccessLongan flower proanthocyanidins induce apoptosis in HT-29 colorectal carcinoma spheroids
Author(s) -
YuanChiang Chung,
Hua-Che Chiang,
Hsin-Li Chang,
ChihCheng Lin,
Li-Tsai Lo,
Ai-Yih Wang,
KanSen Chou,
ChihPing Hsu
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.176170
Subject(s) - apoptosis , annexin , cancer research , protein kinase b , spheroid , cell growth , epidermal growth factor receptor , biology , pi3k/akt/mtor pathway , chemistry , in vitro , receptor , biochemistry
Proanthocyanidin-rich longan flower extract (LFP) has been previously shown to inhibit the proliferation and anchorage-independent growth in soft agar of two colorectal carcinoma (CRC) cells in vitro. In this report, we further examined the effects of LFP in a CRC spheroid model.