Promoter methylation of human mutL homolog 1 and colorectal cancer risk | Zendy

Bian Shi | Zendy; Junfeng Chu | Zendy; Qilong Gao | Zendy; Tong-de Tian | Zendy

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Promoter methylation of human mutL homolog 1 and colorectal cancer risk

Author(s) -

Bian Shi,

Junfeng Chu,

Qilong Gao,

Tong-de Tian

Publication year - 2018

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.172587

Subject(s) - meta analysis , methylation , odds ratio , publication bias , confidence interval , medicine , colorectal cancer , subgroup analysis , dna methylation , oncology , relative risk , gastroenterology , cancer , biology , genetics , gene , gene expression

Several studies suggested that promoter methylation of human mutL homolog 1 (hMLH1) was associated with the risk of colorectal cancer (CRC). However, other studies did not indicate the same results. To derive a more comprehensive estimation of the association between hMLH1 methylation and CRC risk, we conducted a meta-analysis.

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