Open AccessDual-specificity phosphatase 6 genetic variants associated with risk of lung squamous cell carcinoma in Han Chinese
Author(s) -
Tianlu Wang,
Yu Song,
Yong Ren,
Baosen Zhou,
He-Tong Wang,
Ya Gao,
Haifeng Yu,
Yong Zhao
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.172108
Subject(s) - genotype , lung cancer , single nucleotide polymorphism , medicine , adenocarcinoma , linkage disequilibrium , population , oncology , biology , gastroenterology , cancer , gene , genetics , environmental health
Nonsmall cell lung cancer (NSCLC) mainly contains adenocarcinoma (AC) and squamous cell carcinoma (SqCC). This study investigated single nucleotide polymorphism (SNP) of topoisomerase II alpha (TOP2A) and dual-specificity phosphatase 6 (DUSP6) in a hospital-based case and control cohort of individuals for association with risk of different histological subtypes of NSCLC.